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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Adenosine receptor A2a
(Homo sapiens (Human))
University Of Camerino
Curated by
ChEMBL
Ligand
BDBM50009697
(2-(6-Amino-purin-9-yl)-ethanol | 9-(2-Hydroxyethyl...)
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Affinity Data
Ki: 1.10E+4nM
Assay Description:
Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
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Target
Adenosine receptor A2a/A2b
(Rattus norvegicus)
University Of South Florida
Curated by
ChEMBL
Ligand
BDBM50009697
(2-(6-Amino-purin-9-yl)-ethanol | 9-(2-Hydroxyethyl...)
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Affinity Data
Ki: 1.20E+4nM
Assay Description:
Tested for inhibition of rat PC12 adenylate cyclase stimulation by using NECA as a radioligand
More data for this Ligand-Target Pair
Target Info
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Target
Adenosine receptor A1
(Homo sapiens (Human))
University Of Camerino
Curated by
ChEMBL
Ligand
BDBM50009697
(2-(6-Amino-purin-9-yl)-ethanol | 9-(2-Hydroxyethyl...)
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Affinity Data
Ki: 2.90E+4nM
Assay Description:
Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Target
Adenosine receptor A2b
(Homo sapiens (Human))
University Of Camerino
Curated by
ChEMBL
Ligand
BDBM50009697
(2-(6-Amino-purin-9-yl)-ethanol | 9-(2-Hydroxyethyl...)
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Affinity Data
Ki: >3.00E+4nM
Assay Description:
Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activity
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
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KEGG
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antibodypedia
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Target
Adenosine receptor A2a/A2b
(Rattus norvegicus)
University Of South Florida
Curated by
ChEMBL
Ligand
BDBM50009697
(2-(6-Amino-purin-9-yl)-ethanol | 9-(2-Hydroxyethyl...)
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Affinity Data
Ki: 4.60E+4nM
Assay Description:
Binding affinity against adenosine A2 receptor in rat striatum by using [3H]NECA as a radioligand
More data for this Ligand-Target Pair
Target Info
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Target
Adenosine receptor A1
(Rattus norvegicus (rat))
University Of South Florida
Curated by
ChEMBL
Ligand
BDBM50009697
(2-(6-Amino-purin-9-yl)-ethanol | 9-(2-Hydroxyethyl...)
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Affinity Data
Ki: >1.00E+5nM
Assay Description:
Binding affinity against adenosine A1 receptor in rat cortex by using [3H]- PIA as a radioligand
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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CHEMBL
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Target
Adenosine receptor A3
(Homo sapiens (Human))
University Of Camerino
Curated by
ChEMBL
Ligand
BDBM50009697
(2-(6-Amino-purin-9-yl)-ethanol | 9-(2-Hydroxyethyl...)
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Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
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Target
Replicase polyprotein 1ab
(2019-nCoV)
Cornell University
Ligand
BDBM50009697
(2-(6-Amino-purin-9-yl)-ethanol | 9-(2-Hydroxyethyl...)
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Affinity Data
IC50: 1.82E+3nM
Assay Description:
IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Toll-like receptor 7
(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by
ChEMBL
Ligand
BDBM50009697
(2-(6-Amino-purin-9-yl)-ethanol | 9-(2-Hydroxyethyl...)
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Affinity Data
IC50: 6.84E+5nM
Assay Description:
Antagonist activity at TLR7 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI