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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
13
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Target
Adenosine deaminase
(Bos taurus (bovine))
Academia Sinica
Curated by
ChEMBL
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
Ki: >8.00E+5nM
Assay Description:
Inhibitory activity against adenosine deaminase
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Target Info
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Target
Phosphoribosyl pyrophosphate synthase-associated protein 2
(Homo sapiens (Human))
Academia Sinica
Curated by
ChEMBL
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
Ki: 3.00E+6nM
Assay Description:
Inhibitory activity against PRPP synthetase
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Target Info
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antibodypedia
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Target
Solute carrier family 22 member 6
(Homo sapiens (Human))
Gilead Sciences
Curated by
ChEMBL
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
IC50: 2.80E+4nM
Assay Description:
TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cells
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Target Info
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Reactome pathway
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antibodypedia
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Target
Ribose-phosphate pyrophosphokinase 1
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
IC50: 3.20E+6nM
Assay Description:
Inhibitory concentration against Escherichia coli Pyrophosphate Synthetase (PRPP)
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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Target
Thymidine kinase
(Human herpesvirus 3)
Academy Of Sciences Of The Czech Republic
Curated by
ChEMBL
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
EC50: 6.58E+4nM
Assay Description:
Inhibition of varicella zoster virus thymidine kinase (VZV TK+) YS/R strain
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Target
Thymidine kinase
(Human herpesvirus 3)
Academy Of Sciences Of The Czech Republic
Curated by
ChEMBL
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
EC50: 3.11E+4nM
Assay Description:
Inhibitory activity against varicella zoster virus thymidine kinase (VZV TK+) OKA strain
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Target
Thymidine kinase
(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Academy Of Sciences Of The Czech Republic
Curated by
ChEMBL
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
EC50: 1.83E+4nM
Assay Description:
Inhibitory activity against herpes simplex virus type 1 (HSV-1) thymidine kinase (TK) VMW 1837 strain
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Target
Thymidine kinase
(Human herpesvirus 3)
Academy Of Sciences Of The Czech Republic
Curated by
ChEMBL
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
EC50: 1.97E+4nM
Assay Description:
Inhibitory activity against varicella zoster virus thymidine kinase (VZV TK+) YS strain
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Target
Thymidine kinase
(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Academy Of Sciences Of The Czech Republic
Curated by
ChEMBL
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
EC50: 4.75E+4nM
Assay Description:
Inhibition of herpes simplex virus type 1 thymidine kinase (HSV-1 TK-) B2006 strain
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Target
Capsid scaffolding protein
(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
The Regents Of The University Of California
US Patent
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
EC50: 5.50E+4nM
Assay Description:
Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...
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Target
HIV-1 protease
(Human immunodeficiency virus)
The Regents Of The University Of California
US Patent
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
EC50: 1.60E+4nM
Assay Description:
Preliminary experiments in the inhibition of HIV-1 replication by invention compounds were performed as follows. Drug assays were carried out as prev...
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Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
The Regents Of The University Of California
US Patent
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
EC50: 5.50E+4nM
Assay Description:
Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...
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Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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Target
Capsid protein
(Hepatitis B virus)
Sunshine Lake Pharma
Curated by
ChEMBL
Ligand
BDBM50001103
((2-(6-amino-9H-purin-9-yl)ethoxy)methylphosphonic ...)
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Affinity Data
EC50: 83nM
Assay Description:
Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...
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CHEMBL
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