Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCyclin-C(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50265277(4-phenoxy-2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin...)Copy SMILESCopy InChI

Affinity DataIC50:  8.30nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL

LigandBDBM50265277(4-phenoxy-2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin...)Copy SMILESCopy InChI

Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human recombinant COT by HTRF-based assayMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI