Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
DNA ligase 1
(Homo sapiens (Human))
The Scripps Research Institute
Ligand
BDBM23076
(3-(4-benzylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.20nM ΔG°: -48.5kJ/mole IC50: 3nM
T: 2°C
Assay Description:
The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM23076
(3-(4-benzylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.20nM
Assay Description:
Inhibition of rat recombinant FAAH expressed in Escherichia coli
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carboxylic ester hydrolase
(Homo sapiens (Human))
The Scripps Research Institute
Ligand
BDBM23076
(3-(4-benzylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 900nM
T: 2°C
Assay Description:
Inhibition of TGH activity was assayed using COS-7 expressed TGH and the chromogenic substrate. IC50 values were determined from the inhibition obser...
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI