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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50332086
(2-(isoquinolin-5-yl)-N-(2-(thiazol-4-yl)thiophen-3...)
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Affinity Data
IC50: 140nM
Assay Description:
Inhibition of recombinant JNK1 after 60 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50332086
(2-(isoquinolin-5-yl)-N-(2-(thiazol-4-yl)thiophen-3...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 160nM
Assay Description:
Inhibition of recombinant JNK3 after 60 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50332086
(2-(isoquinolin-5-yl)-N-(2-(thiazol-4-yl)thiophen-3...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 270nM
Assay Description:
Inhibition of recombinant JNK2 after 60 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50332086
(2-(isoquinolin-5-yl)-N-(2-(thiazol-4-yl)thiophen-3...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.05E+3nM
Assay Description:
(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
US Patent
Copy BDB DOI
Target
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50332086
(2-(isoquinolin-5-yl)-N-(2-(thiazol-4-yl)thiophen-3...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.05E+3nM
Assay Description:
(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
US Patent
Copy BDB DOI
Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50332086
(2-(isoquinolin-5-yl)-N-(2-(thiazol-4-yl)thiophen-3...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.05E+3nM
Assay Description:
(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
US Patent
Copy BDB DOI
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50332086
(2-(isoquinolin-5-yl)-N-(2-(thiazol-4-yl)thiophen-3...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of recombinant p38alpha after 60 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Elan Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50332086
(2-(isoquinolin-5-yl)-N-(2-(thiazol-4-yl)thiophen-3...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of recombinant Erk2 after 60 mins by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI