Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Axovant Sciences

US Patent

LigandBDBM322432((R)-7-phenyl-N-(1'-azaspiro[cyclopropane-1,2'-bicy...)Copy SMILESCopy InChI

Affinity DataKi:  30nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences

US Patent

LigandBDBM322432((R)-7-phenyl-N-(1'-azaspiro[cyclopropane-1,2'-bicy...)Copy SMILESCopy InChI

Affinity DataKi:  310nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI