Home
About
Info
Download
WebServices
Contact
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Mitogen-activated protein kinase 1
(Mus musculus (Mouse))
Merck Sharp & Dohme
US Patent
Ligand
BDBM203308
(US9242981, 37)
Copy SMILES
Affinity Data
IC50: 1.16nM
Assay Description:
Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 14 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Mitogen-activated protein kinase 1
(Mus musculus (Mouse))
Merck Sharp & Dohme
US Patent
Ligand
BDBM203308
(US9242981, 37)
Copy SMILES
Affinity Data
Kd: 6nM
T: 2°C
Assay Description:
The SAR (Structure Activity Relationship) for ERK ligands covered by this invention was interrogated using the TdF (Temperature Dependence Fluoresc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI