Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL

LigandBDBM50439537(CHEMBL2418356)Copy SMILESCopy InChI

Affinity DataIC50:  550nMAssay Description:Negative allosteric modulation of human mGlu1 receptor expressed in HEK293A TREx cells assessed as calcium flux after 45 minsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL

LigandBDBM50439537(CHEMBL2418356)Copy SMILESCopy InChI

Affinity DataIC50:  553nMAssay Description:Negative allosteric modulation of human mGlu1 receptor expressed in HEK293A TREx cells assessed as calcium flux after 45 minsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI