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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Xiamen University

US Patent
LigandPNGBDBM319828(US10174015, Compound 41)
Affinity DataIC50:  680nMAssay Description:In the Experimental example, endocannabinoid hydrolases used were Fatty Acid Amide Hydrolase (FAAH) and N-acylethanolamide hydrolyzing acid amidase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM319828(US10174015, Compound 41)
Affinity DataIC50:  680nMAssay Description:Inhibition of rat NAAA expressed in HEK293 cells using heptadecenoylethanolamide as substrate after 30 mins by HPLC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Xiamen University

US Patent
LigandPNGBDBM319828(US10174015, Compound 41)
Affinity DataIC50: >1.00E+5nMAssay Description:In the Experimental example, endocannabinoid hydrolases used were Fatty Acid Amide Hydrolase (FAAH) and N-acylethanolamide hydrolyzing acid amidase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent