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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50317216
((2R)-N-(adamantan-2-yl)-1-(cyclohexylmethyl)pyrrol...)
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Affinity Data
Ki: 2.40nM
Assay Description:
Inhibition of human 11-beta-HSD1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50317216
((2R)-N-(adamantan-2-yl)-1-(cyclohexylmethyl)pyrrol...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.5nM
Assay Description:
Inhibition of mouse 11-beta-HSD1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50317216
((2R)-N-(adamantan-2-yl)-1-(cyclohexylmethyl)pyrrol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.320nM
Assay Description:
Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI