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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
1
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Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Novartis
Ligand
BDBM30314
(Pyrrolo-pyrimidone, 7)
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Affinity Data
IC50: 190nM
pH: 7.5 T: 2°C
Assay Description:
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...
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