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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173953(CHEMBL364069 | N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50170587(5-Pyridin-2-yl-thiophene-2-carboxylic acid (1-aza-...)
Affinity DataKi:  6.90nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50170587(5-Pyridin-2-yl-thiophene-2-carboxylic acid (1-aza-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against Nicotinic acetylcholine receptor alpha4-beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed