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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50156065
(CHEMBL191039 | N-(1,3-diphenyl-1H-pyrazol-5-yl)ben...)
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Affinity Data
Ki: 4.18E+3nM
Assay Description:
Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50156065
(CHEMBL191039 | N-(1,3-diphenyl-1H-pyrazol-5-yl)ben...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 203nM
Assay Description:
Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Vanderbilt University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50156065
(CHEMBL191039 | N-(1,3-diphenyl-1H-pyrazol-5-yl)ben...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 300nM
Assay Description:
Effective concentration against metabotropic glutamate receptor 5 of rat
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50156065
(CHEMBL191039 | N-(1,3-diphenyl-1H-pyrazol-5-yl)ben...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 40nM
Assay Description:
Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI