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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Janssen Research And Development
Curated by
ChEMBL
Ligand
BDBM50443141
(CHEMBL3085983 | US9221797, 44)
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Affinity Data
IC50: 3.20nM
Assay Description:
Inhibition of FMS (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Macrophage colony-stimulating factor 1 receptor [555-568]
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM50443141
(CHEMBL3085983 | US9221797, 44)
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Affinity Data
IC50: 4.60nM
pH: 7.5
Assay Description:
A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Macrophage colony-stimulating factor 1 receptor
(Mus musculus (Mouse))
Janssen Research And Development
Curated by
ChEMBL
Ligand
BDBM50443141
(CHEMBL3085983 | US9221797, 44)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of FMS in mouse BMDM cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI