Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL

LigandBDBM50382806(CHEMBL2023197)Copy SMILESCopy InChI

Affinity DataIC50:  280nMAssay Description:Inhibition of PDK1 assessed as [gamma-33P]ATP incorporation into substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL

LigandBDBM50382806(CHEMBL2023197)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2 using RbING as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI