Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50209153(CHEMBL247389 | furan-2-carboxylic acid (3-thiophen...)Copy SMILESCopy InChI

Affinity DataIC50:  90nMAssay Description:Inhibition of Flt1 by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50209153(CHEMBL247389 | furan-2-carboxylic acid (3-thiophen...)Copy SMILESCopy InChI

Affinity DataIC50:  110nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50209153(CHEMBL247389 | furan-2-carboxylic acid (3-thiophen...)Copy SMILESCopy InChI

Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI