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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetAdenosine receptor A2b(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336975(CHEMBL1672621 | N-(6-Pyridin-3-yl-5-pyridin-4-ylpy...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336975(CHEMBL1672621 | N-(6-Pyridin-3-yl-5-pyridin-4-ylpy...)
Affinity DataKi:  312nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HeLa cells after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336975(CHEMBL1672621 | N-(6-Pyridin-3-yl-5-pyridin-4-ylpy...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336975(CHEMBL1672621 | N-(6-Pyridin-3-yl-5-pyridin-4-ylpy...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336975(CHEMBL1672621 | N-(6-Pyridin-3-yl-5-pyridin-4-ylpy...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336975(CHEMBL1672621 | N-(6-Pyridin-3-yl-5-pyridin-4-ylpy...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed