Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 5 hits in this display
BDBM104729(US8569308, 149 | US8569308, 223)
IC50: 520nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair
BDBM104729(US8569308, 149 | US8569308, 223)
IC50: 708nMAssay Description:Negative allosteric modulator activity at rat mGlu5 expressed in HEK293A cells assessed as reduction in glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
BDBM104729(US8569308, 149 | US8569308, 223)
IC50: 709nMAssay Description:Negative allosteric modulator activity at rat mGlu5 expressed in HEK293A cells assessed as reduction in glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
BDBM104729(US8569308, 149 | US8569308, 223)
IC50: 794nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair
BDBM104729(US8569308, 149 | US8569308, 223)
IC50: 794nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair