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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105084(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...)
Affinity DataIC50:  652nMAssay Description:Inhibition of human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105084(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105084(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...)
Affinity DataIC50:  1.81E+3nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105084(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...)
Affinity DataIC50:  1.81E+3nMAssay Description:Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105084(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...)
Affinity DataIC50:  2.08E+3nMAssay Description:Inhibition of human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105084(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...)
Affinity DataIC50:  2.94E+3nMAssay Description:Binding affinity against dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105084(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105084(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed