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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
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Found
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Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50337529
((E)-7-styryl-2H-pyrano[2,3-b]pyridin-4(3H)-one | C...)
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Affinity Data
EC50: 240nM
Assay Description:
Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...
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