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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxy-corticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  10.3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  10.3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  24nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells using deoxycorticosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  24nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxy-corticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  228nMAssay Description:Inhibition of human placental CYP19 using androstenedione substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  228nMAssay Description:Inhibition of human CYP19 using [1beta-3H]androstenedione as substrate by 3H2O methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50395455(CHEMBL2163639)
Affinity DataIC50:  2.88E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed