Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetD(2) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50388680(CHEMBL2059307)Copy SMILESCopy InChI

Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [3H]raclopride from human D2L receptor expressed in CHO cells after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50388680(CHEMBL2059307)Copy SMILESCopy InChI

Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells after 30 mins by Rb+ flux assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL

LigandBDBM50388680(CHEMBL2059307)Copy SMILESCopy InChI

Affinity DataEC50:  12nMAssay Description:Agonist activity at human M1 receptor expressed in CHO-K1 cells assessed as calcium mobilization for 6 mins by Calcium4-based stainingMore data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI