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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
Bristol-Myers
Curated by
ChEMBL
Ligand
BDBM50016955
(4-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-...)
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Affinity Data
IC50: 1.10nM
Assay Description:
Ability to bind at alpha-1 adrenergic receptor by displacing [3H]WB-4101
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
Bristol-Myers
Curated by
ChEMBL
Ligand
BDBM50016955
(4-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-...)
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Affinity Data
IC50: 1.20nM
Assay Description:
Ability to bind at serotonin 5-hydroxytryptamine 1A receptors of rat hippocampus by displacing [3H]8-OH-DPAT
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
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Target
Serotonin 2 (5-HT2) receptor
(RAT)
Bristol-Myers
Curated by
ChEMBL
Ligand
BDBM50016955
(4-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-...)
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Affinity Data
IC50: 6.70nM
Assay Description:
Ability to bind at serotonin 5-hydroxytryptamine 2 receptors of rat hippocampus by displacing [3H]spiperone
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Bristol-Myers
Curated by
ChEMBL
Ligand
BDBM50016955
(4-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-...)
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Affinity Data
IC50: 608nM
Assay Description:
Ability to bind at Dopamine receptor D2 of rat corpus striatum by displacing [3H]spiperone
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI