Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Nociceptin receptor
(Homo sapiens (Human))
Sri International
Curated by
ChEMBL
Ligand
BDBM50147749
(1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6nM
Assay Description:
Binding affinity against human Nociceptin receptor on CHO cell membranes by [3H]N/OFQ displacement.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nociceptin receptor
(Homo sapiens (Human))
Sri International
Curated by
ChEMBL
Ligand
BDBM50147749
(1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6nM
Assay Description:
Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Sri International
Curated by
ChEMBL
Ligand
BDBM50147749
(1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 14nM
Assay Description:
Binding affinity against human Opioid receptor mu 1 on CHO cell membranes was determined by [3H]DAMGO displacement.
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Sri International
Curated by
ChEMBL
Ligand
BDBM50147749
(1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 229nM
Assay Description:
Binding affinity against human Opioid receptor kappa 1 on CHO cell membranes by [3H]U-69593 displacement.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
Sri International
Curated by
ChEMBL
Ligand
BDBM50147749
(1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity against human opioid receptor delta 1 transfected on CHO cells was determined using [3H]Cl-DPDPE
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nociceptin receptor
(Homo sapiens (Human))
Sri International
Curated by
ChEMBL
Ligand
BDBM50147749
(1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Concentration required for stimulation of [35S]-GTP-gammaS, binding NOP receptor in cell membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI