Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Oxysterols receptor LXR-alpha
(Homo sapiens (Human))
University Of Tokyo
Ligand
BDBM23840
(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.80E+3nM
T: 2°C
Assay Description:
Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Oxysterols receptor LXR-alpha
(Homo sapiens (Human))
University Of Tokyo
Ligand
BDBM23840
(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.80E+3nM
Assay Description:
Antagonist activity at human recombinant LXRalpha expressed in HEK293 cells assessed as inhibition of T0901317-induced transcriptional activation by ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Oxysterols receptor LXR-alpha
(Homo sapiens (Human))
University Of Tokyo
Ligand
BDBM23840
(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.80E+3nM
Assay Description:
Antagonist activity at human LXRalpha expressed in HEK293 cells assessed as inhibition of beta-galactosidase activity by luciferase reporter gene ass...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Oxysterols receptor LXR-alpha
(Homo sapiens (Human))
University Of Tokyo
Ligand
BDBM23840
(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.30E+4nM
Assay Description:
Antagonist activity at human LXR-alpha transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay in presence of 0.3 uM N-(4-(1,1,1,3...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-glucosidase MAL32
(Saccharomyces cerevisiae)
University Of Tokyo
Ligand
BDBM23840
(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.62E+4nM
pH: 7.0 T: 2°C
Assay Description:
The alpha-glucosidase inhibitory activity of test compounds was determined in a 96-well plate format. The reaction mixture containing enzyme and chro...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Oxysterols receptor LXR-beta
(Homo sapiens (Human))
The University Of Tokyo
Curated by
ChEMBL
Ligand
BDBM23840
(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Antagonist activity at human LXRbeta expressed in HEK293 cells assessed as inhibition of beta-galactosidase activity by luciferase reporter gene assa...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Oxysterols receptor LXR-beta
(Homo sapiens (Human))
The University Of Tokyo
Curated by
ChEMBL
Ligand
BDBM23840
(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Antagonist activity at human LXR-beta transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay in presence of 0.1 uM N-(4-(1,1,1,3,...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Oxysterols receptor LXR-beta
(Homo sapiens (Human))
The University Of Tokyo
Curated by
ChEMBL
Ligand
BDBM23840
(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.40E+4nM
Assay Description:
Human embryonic kidney (HEK) 293 cells were cultured in D-MEM medium. Transfections were performed by the calcium phosphate coprecipitation method. T...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Oxysterols receptor LXR-beta
(Homo sapiens (Human))
The University Of Tokyo
Curated by
ChEMBL
Ligand
BDBM23840
(2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.40E+4nM
Assay Description:
Antagonist activity at human recombinant LXRbeta expressed in HEK293 cells assessed as inhibition of T0901317-induced transcriptional activation by l...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI