Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 24 hits in this display
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
Ki: 4.40E+3nMAssay Description:Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
IC50: 301nMAssay Description:A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...More data for this Ligand-Target Pair
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
IC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer p...More data for this Ligand-Target Pair
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
IC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer p...More data for this Ligand-Target Pair
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
IC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer p...More data for this Ligand-Target Pair
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
IC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer p...More data for this Ligand-Target Pair
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
IC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer p...More data for this Ligand-Target Pair
BDBM65457((-)-Thalidomide | (S)-Thalidomide)
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
IC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer p...More data for this Ligand-Target Pair
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
IC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer p...More data for this Ligand-Target Pair
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
IC50: 2.29E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence in pr...More data for this Ligand-Target Pair
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
BDBM65362((+)-Thalidomide | (R)-(+)-thalidomide | (R)-Thalid...)
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
BDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)