Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL

LigandBDBM50374930(CHEMBL257458)Copy SMILESCopy InChI

Affinity DataIC50:  260nMAssay Description:Inhibition of human integrin alpha-4-beta-7-MAdCAM interaction in human RPMI 8866 cells by whole-cell adhesion assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL

LigandBDBM50374930(CHEMBL257458)Copy SMILESCopy InChI

Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of integrin alpha-5-beta-1-fibronectin interactionMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL

LigandBDBM50374930(CHEMBL257458)Copy SMILESCopy InChI

Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of integrin alpha-4-beta-1-VCAM interactionMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI