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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104618(CHEMBL3593552)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104618(CHEMBL3593552)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP8 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104618(CHEMBL3593552)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP14 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104618(CHEMBL3593552)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP9 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104618(CHEMBL3593552)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP2 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104618(CHEMBL3593552)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed