Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50327625(6-(3-(4-(2,3-dihydrobenzofuran-4-yl)piperazin-1-yl...)Copy SMILESCopy InChI

Affinity DataKi:  1.46nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50327625(6-(3-(4-(2,3-dihydrobenzofuran-4-yl)piperazin-1-yl...)Copy SMILESCopy InChI

Affinity DataKi:  4.29nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50327625(6-(3-(4-(2,3-dihydrobenzofuran-4-yl)piperazin-1-yl...)Copy SMILESCopy InChI

Affinity DataKi:  12.1nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI