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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283788(5-(1-Aza-bicyclo[2.2.2]oct-2-en-3-yl)-thiophene-2-...)
Affinity DataKi:  990nMAssay Description:In vitro binding affinity of the compound towards muscarinic receptor in cerebral cortex (M1) was determinedMore data for this Ligand-Target Pair
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TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283788(5-(1-Aza-bicyclo[2.2.2]oct-2-en-3-yl)-thiophene-2-...)
Affinity DataKi:  2.60E+3nMAssay Description:In vitro binding affinity of the compound towards muscarinic receptor in heart (M2) was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283788(5-(1-Aza-bicyclo[2.2.2]oct-2-en-3-yl)-thiophene-2-...)
Affinity DataKi:  4.80E+3nMAssay Description:In vitro binding affinity towards muscarinic receptor in parotid gland (M3)More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283788(5-(1-Aza-bicyclo[2.2.2]oct-2-en-3-yl)-thiophene-2-...)
Affinity DataKi:  5.70E+3nMAssay Description:In vitro binding affinity towards muscarinic receptor in urinary bladder was determinedMore data for this Ligand-Target Pair
In DepthDetails Article