Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50356445(CHEMBL1911701)
Affinity DataIC50:  12nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]-cortisone to [3H]-cortisol by scintillation plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50356445(CHEMBL1911701)
Affinity DataIC50:  105nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50356445(CHEMBL1911701)
Affinity DataIC50:  270nMAssay Description:Inhibition of 11beta-HSD1 in human HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50356445(CHEMBL1911701)
Affinity DataIC50:  3.97E+3nMAssay Description:Inhibition of 11beta-HSD1 in mouse 3T3L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed