Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Pharmazeutische Chemie

Curated by ChEMBL

LigandBDBM50042216(8-Phenyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dion...)Copy SMILESCopy InChI

Affinity DataKi:  210nMAssay Description:Binding affinity at Adenosine A1 receptor in rat brain cortical membrane using [3H]-N6-R-phenylisopropyladenosine (R-PIA) as radioligandMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pharmazeutische Chemie

Curated by ChEMBL

LigandBDBM50042216(8-Phenyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dion...)Copy SMILESCopy InChI

Affinity DataKi:  730nMAssay Description:Binding affinity against Adenosine A2 receptor in rat striatal membranes using [3H]5'-(N-ethylcarboxamido)-adenosine (NECA) as the ligandMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI