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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
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Found
1
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Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50337504
(6-(phenylethynyl)isoquinolin-1(2H)-one | CHEMBL168...)
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Affinity Data
EC50: 182nM
Assay Description:
Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...
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