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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
18
hits in this display
Target
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
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Affinity Data
Ki: 2.60nM
Assay Description:
Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cells
More data for this Ligand-Target Pair
Target Info
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Target
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.60nM
Assay Description:
Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells
More data for this Ligand-Target Pair
Target Info
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Target
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.60nM
Assay Description:
Displacement of [3H]4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one from MCH-1 receptor expressed in CHO-K1 cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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Article
PubMed
Copy BDB DOI
Target
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
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Copy InChI
Affinity Data
IC50: 14nM
Assay Description:
Antagonistic activity at MCH-1 receptor expressed in CHO-K1 cell assessed as inhibition of MCH-induced calcium release
More data for this Ligand-Target Pair
Target Info
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
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Affinity Data
IC50: 2.50E+3nM
Assay Description:
Inhibition of human ERG expressed in HEK cells by mini-patch clamp assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
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antibodypedia
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
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DrugBank
antibodypedia
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Ligand Info
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2D6
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
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CHEMBL
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C19
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Ligand Info
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CHEMBL
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Article
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP1A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
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Ligand Info
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CHEMBL
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2B6
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2B6
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of CYP3A4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP1A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2B6
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2B6
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C19
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of CYP3A4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2D6
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human))
Amri
Curated by
ChEMBL
Ligand
BDBM50331161
(4-(benzyloxy)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-i...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.42nM
Assay Description:
Binding affinity to MCH-1 receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI