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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
Ici Pharmaceuticals Group
Curated by
ChEMBL
Ligand
BDBM50009006
(2-Naphthalen-2-ylmethyl-1,2-dihydro-indazol-3-one ...)
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Affinity Data
IC50: 970nM
Assay Description:
In vitro inhibition of LTB4 production was measured in rat blood
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Prostaglandin G/H synthase 1/2
(RAT)
Ici Pharmaceuticals Group
Curated by
ChEMBL
Ligand
BDBM50009006
(2-Naphthalen-2-ylmethyl-1,2-dihydro-indazol-3-one ...)
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Affinity Data
IC50: 1.80E+4nM
Assay Description:
In vitro inhibition of PGE-2 production was measured in rat blood
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Ici Pharmaceuticals Group
Curated by
ChEMBL
Ligand
BDBM50009006
(2-Naphthalen-2-ylmethyl-1,2-dihydro-indazol-3-one ...)
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Copy InChI
Affinity Data
EC50: >3.64E+5nM
Assay Description:
Ex vivo inhibition of LTB4 production was measured in dog blood
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI