Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Mannan-binding lectin serine protease 2
(Homo sapiens)
Omeros
US Patent
Ligand
BDBM222117
(2-(2-Thienyl)-4H-3,1-benzoxazin-4-one (4) | US1158...)
Copy SMILES
Copy InChI
Affinity Data
Ki: <1.00E+3nM
Assay Description:
The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Chymotrypsinogen A
(Bos taurus (bovine))
University Of Karachi
Ligand
BDBM222117
(2-(2-Thienyl)-4H-3,1-benzoxazin-4-one (4) | US1158...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.10E+3nM
Assay Description:
The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A1
(Rattus norvegicus (rat))
North-West University
Curated by
ChEMBL
Ligand
BDBM222117
(2-(2-Thienyl)-4H-3,1-benzoxazin-4-one (4) | US1158...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.24E+4nM
Assay Description:
Displacement of [3H]DPCPX from Sprague-Dawley rat whole brain membrane A1AR by scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Omeros
US Patent
Ligand
BDBM222117
(2-(2-Thienyl)-4H-3,1-benzoxazin-4-one (4) | US1158...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.25E+4nM
Assay Description:
The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Adenosine receptor A2a
(Rattus norvegicus (rat))
North-West University
Curated by
ChEMBL
Ligand
BDBM222117
(2-(2-Thienyl)-4H-3,1-benzoxazin-4-one (4) | US1158...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H]NECA from Sprague-Dawley rat striatal membrane A2A adenosine receptor by scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Chymotrypsinogen A
(Bos taurus (bovine))
University Of Karachi
Ligand
BDBM222117
(2-(2-Thienyl)-4H-3,1-benzoxazin-4-one (4) | US1158...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.21E+4nM
pH: 7.6
Assay Description:
The α-chymotrypsin inhibition activity was evaluated in 50 mM Tris-HCl buffer pH 7.6 with 10 mM CaCl2. α-Chymotrypsin (bovine pancreas) at ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI