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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Beta-lactamase
(Escherichia coli)
Northwestern University Medical School
Curated by
ChEMBL
Ligand
BDBM50067887
(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
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Affinity Data
Ki: 1.70E+3nM
Assay Description:
Inhibitory activity against E. coli AmpC beta-lactamase.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
Beta-lactamase
(Escherichia coli)
Northwestern University Medical School
Curated by
ChEMBL
Ligand
BDBM50067887
(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
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Copy InChI
Affinity Data
Ki: 1.70E+3nM
Assay Description:
Binding affinity of the compound towards AmpC beta-lactamase binding site from Escherichia coli
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Subtilisin Carlsberg
(Bacillus licheniformis)
TBA
Curated by
ChEMBL
Ligand
BDBM50067887
(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
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Affinity Data
Ki: 8.00E+3nM
Assay Description:
Competitive inhibition of Subtilisin Carlsberg enzyme from B. lentus
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
Copy BDB DOI
Target
Subtilisin BL
(Bacillus lentus)
TBA
Curated by
ChEMBL
Ligand
BDBM50067887
(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
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Affinity Data
Ki: 1.50E+4nM
Assay Description:
Competitive inhibition of Subtilisin BL M222C-mutated enzyme from B. lentus
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
Copy BDB DOI
Target
Subtilisin BL
(Bacillus lentus)
TBA
Curated by
ChEMBL
Ligand
BDBM50067887
(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
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Copy InChI
Affinity Data
Ki: 2.70E+4nM
Assay Description:
Competitive inhibition of Subtilisin BL wild type enzyme from B. lentus
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
Copy BDB DOI
Target
Subtilisin BL
(Bacillus lentus)
TBA
Curated by
ChEMBL
Ligand
BDBM50067887
(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
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Copy InChI
Affinity Data
Ki: 3.80E+4nM
Assay Description:
Competitive inhibition of Subtilisin BL M222S-mutated enzyme from B. lentus
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
Copy BDB DOI
Target
Beta-lactamase TEM
(Escherichia coli)
TBA
Curated by
ChEMBL
Ligand
BDBM50067887
(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
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Affinity Data
Ki: 1.21E+5nM
Assay Description:
Inhibitory constant was determined against class A RTEM-1 Beta-lactamase from Escherichia coli
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
Copy BDB DOI
Target
Beta-lactamase
(Escherichia coli)
Northwestern University Medical School
Curated by
ChEMBL
Ligand
BDBM50067887
(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
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Copy InChI
Affinity Data
IC50: 5.00E+3nM
Assay Description:
Compound was tested for its specificity against AmpC beta-lactamase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Trypsin-2
(Homo sapiens (Human))
Northwestern University Medical School
Curated by
ChEMBL
Ligand
BDBM50067887
(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
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Affinity Data
IC50: >2.00E+5nM
Assay Description:
Compound was tested for its specificity against beta-trypsin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Chymotrypsinogen A
(Bos taurus (bovine))
Northwestern University Medical School
Curated by
ChEMBL
Ligand
BDBM50067887
(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
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Copy InChI
Affinity Data
IC50: >2.00E+5nM
Assay Description:
Compound was tested for its specificity against alpha-chymotrypsin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI