Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096775(CHEMBL431678 | Cyanoguanidine derivative)
Affinity DataIC50:  65nMAssay Description:Binding affinity for human Beta-1 adrenergic receptor using [125I]-iodocyanopindolol as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096775(CHEMBL431678 | Cyanoguanidine derivative)
Affinity DataIC50:  180nMAssay Description:Binding affinity to the human beta-2 adrenergic receptor assayed using [125I]-iodocyanopindolol as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096775(CHEMBL431678 | Cyanoguanidine derivative)
Affinity DataEC50:  13nMAssay Description:In vitro efficacy at human beta-3 adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096775(CHEMBL431678 | Cyanoguanidine derivative)
Affinity DataEC50:  41nMAssay Description:Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed