Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetC-C chemokine receptor-like 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent

LigandBDBM163458(US9062048, 87)Copy SMILESCopy InChI

Affinity DataIC50:  39nMAssay Description:Human monocytic cell line THP-1 cells were obtained from American Type Culture Collection (Manassas, Va., USA). The THP-1 cells were grown in RPMI-16...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL

LigandBDBM50425713(CHEMBL2315938)Copy SMILESCopy InChI

Affinity DataIC50:  39nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL

LigandBDBM50425713(CHEMBL2315938)Copy SMILESCopy InChI

Affinity DataIC50:  3.27E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI