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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
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Target
Bile salt export pump
(Homo sapiens (Human))
University Of Tokyo
Curated by
PDSP K
i
Database
Ligand
BDBM86707
(CAS_147511-69-1 | Pitavastatin)
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Affinity Data
Ki: >1.00E+4nM
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Target Info
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Target
Bile salt export pump
(Rattus norvegicus)
University Of Tokyo
Curated by
PDSP K
i
Database
Ligand
BDBM86707
(CAS_147511-69-1 | Pitavastatin)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
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ChEBI
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Target
3-hydroxy-3-methylglutaryl-coenzyme A reductase
(Rattus norvegicus (rat))
St. John'S University
Curated by
ChEMBL
Ligand
BDBM86707
(CAS_147511-69-1 | Pitavastatin)
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Affinity Data
IC50: 4.10nM
Assay Description:
Inhibition of HMG-CoA reductase in rat liver microsomes assessed as reduction in [14C]-HMG-CoA conversion to [14C]-mevalonic acid after 15 mins by co...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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Target
3-hydroxy-3-methylglutaryl-coenzyme A reductase
(Homo sapiens (Human))
Institute Of Pharmaceutical Industry
Curated by
ChEMBL
Ligand
BDBM50371229
(Livalo | PITAVASTATIN CALCIUM | cid_24848419)
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Affinity Data
IC50: 8.90E+3nM
Assay Description:
Inhibition of HMG CoA reductase by spectrophotometry
More data for this Ligand-Target Pair
Target Info
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ChEBI
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Target
3-hydroxy-3-methylglutaryl-coenzyme A reductase
(Rattus norvegicus (rat))
St. John'S University
Curated by
ChEMBL
Ligand
BDBM50371229
(Livalo | PITAVASTATIN CALCIUM | cid_24848419)
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Affinity Data
IC50: 1.06E+4nM
Assay Description:
Inhibition of Holtzman-Sprague-Dawley rat liver HMG CoA reductase after 30 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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ChEBI
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Article
PubMed
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Target
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human))
Southern Research Institute
Curated by
PubChem BioAssay
Ligand
BDBM50371229
(Livalo | PITAVASTATIN CALCIUM | cid_24848419)
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Affinity Data
EC50: >5.00E+4nM
More data for this Ligand-Target Pair
Target Info
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Target
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human))
Xiamen University
Curated by
ChEMBL
Ligand
BDBM50371229
(Livalo | PITAVASTATIN CALCIUM | cid_24848419)
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Affinity Data
Kd: 1.33E+4nM
Assay Description:
Binding affinity to RXRalpha-LBD (unknown origin) measured up to 120 sec by surface plasma resonance method
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Target Info
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KEGG
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Target
Nuclear receptor subfamily 4 group A member 2
(Homo sapiens (Human))
Goethe University Frankfurt
Curated by
ChEMBL
Ligand
BDBM86707
(CAS_147511-69-1 | Pitavastatin)
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Affinity Data
EC50: 120nM
Assay Description:
Agonist activity at human Nurr1 measured by Gal4-Nurr1 hybrid reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
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In Depth
Details
PubMed
Copy BDB DOI