Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetATP-citrate synthase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...)
Affinity DataKi:  700nMAssay Description:Inhibitory activity was tested agianst rat ATP-Citrate Lyase (ACL) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...)
Affinity DataKi:  700nMAssay Description:Inhibitory activity was tested agianst rat ATP-Citrate Lyase (ACL) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...)
Affinity DataKi:  770nMAssay Description:Inhibitory activity against human recombinant ATP-Citrate Lyase (ACL) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...)
Affinity DataKi:  770nMAssay Description:Inhibitory activity against human recombinant ATP-Citrate Lyase (ACL) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human ACLYMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of rat ACLYMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant ACLYMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human ATP citrate lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibitory activity was tested agianst human recombinant ATP-Citrate Lyase (ACL) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed