Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL

LigandBDBM50128372((S)-1-[4-(6-Chloro-benzo[b]thiophen-2-yl)-piperidi...)Copy SMILESCopy InChI

Affinity DataKi:  7.60nMAssay Description:Binding affinity was determined towards 5-hydroxytryptamine 1A receptor receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL

LigandBDBM50128372((S)-1-[4-(6-Chloro-benzo[b]thiophen-2-yl)-piperidi...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Binding affinity towards serotonin [5-HT] reuptake site labeled with [3H]-paroxetine as radioligandMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI