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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Sahmyook University
Curated by
ChEMBL
Ligand
BDBM50304633
(9-(5'-Cyclobutylaminocarbonyl-4'-thio-beta-D-ribof...)
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Affinity Data
Ki: 0.170nM
Assay Description:
Displacement of Fluormone-Pan-PPAR Green from human GST-tagged PPARgamma LBD by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Adenosine receptor A3
(Homo sapiens (Human))
Ewha Womans University
Curated by
ChEMBL
Ligand
BDBM50304633
(9-(5'-Cyclobutylaminocarbonyl-4'-thio-beta-D-ribof...)
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Affinity Data
Ki: 1.17nM
Assay Description:
Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A3
(Homo sapiens (Human))
Ewha Womans University
Curated by
ChEMBL
Ligand
BDBM50304633
(9-(5'-Cyclobutylaminocarbonyl-4'-thio-beta-D-ribof...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.20nM
Assay Description:
Displacement of [125I]I-AB-MECA from human A3 adenosine receptor expressed in CHO cell membranes after 60 mins by gamma counting method
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human))
Sahmyook University
Curated by
ChEMBL
Ligand
BDBM50304633
(9-(5'-Cyclobutylaminocarbonyl-4'-thio-beta-D-ribof...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.60nM
Assay Description:
Displacement of Fluormone-Pan-PPAR Green from human GST-tagged PPARdelta LBD by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A1
(Homo sapiens (Human))
Ewha Womans University
Curated by
ChEMBL
Ligand
BDBM50304633
(9-(5'-Cyclobutylaminocarbonyl-4'-thio-beta-D-ribof...)
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Affinity Data
Ki: 23.6nM
Assay Description:
Displacement of [3H]R-PIA from human adenosine A1 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A1
(Homo sapiens (Human))
Ewha Womans University
Curated by
ChEMBL
Ligand
BDBM50304633
(9-(5'-Cyclobutylaminocarbonyl-4'-thio-beta-D-ribof...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 24nM
Assay Description:
Displacement of [3H]CCPA from human A1 receptor expressed in CHO cell membranes after 60 mins by gamma counting method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Sahmyook University
Curated by
ChEMBL
Ligand
BDBM50304633
(9-(5'-Cyclobutylaminocarbonyl-4'-thio-beta-D-ribof...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 122nM
Assay Description:
Displacement of [3H]CGS21680 from human A2A adenosine receptor expressed in HEK293 cell membranes after 60 mins by gamma counting method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Adenosine receptor A2a
(Homo sapiens (Human))
Sahmyook University
Curated by
ChEMBL
Ligand
BDBM50304633
(9-(5'-Cyclobutylaminocarbonyl-4'-thio-beta-D-ribof...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 122nM
Assay Description:
Displacement of [3H]CGS21680 from human adenosine A2A receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI