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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by
ChEMBL
Ligand
BDBM50254511
(CHEMBL468469 | Naltrexone-6-alpha-ol)
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Affinity Data
Ki: 0.210nM
Assay Description:
Activity at human cloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by
ChEMBL
Ligand
BDBM50254511
(CHEMBL468469 | Naltrexone-6-alpha-ol)
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Affinity Data
Ki: 0.560nM
Assay Description:
Activity at human cloned kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by
ChEMBL
Ligand
BDBM50254511
(CHEMBL468469 | Naltrexone-6-alpha-ol)
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Affinity Data
Ki: 56nM
Assay Description:
Displacement of [3H]Naltrindole form human delta opioid receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Mu-type opioid receptor
(GUINEA PIG)
University Of Washington
Curated by
ChEMBL
Ligand
BDBM50254511
(CHEMBL468469 | Naltrexone-6-alpha-ol)
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Affinity Data
IC50: 1.10nM
Assay Description:
Inhibitory concentration was determined against Opioid receptor mu 1 using [3H]- DAMGO radioligand
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig))
University Of Washington
Curated by
ChEMBL
Ligand
BDBM50254511
(CHEMBL468469 | Naltrexone-6-alpha-ol)
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Affinity Data
IC50: 2.60nM
Assay Description:
Inhibitory concentration against Opioid receptor kappa 1 using [3H]- U-69,593 radioligand
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
Rensselaer Polytechnic Institute
Curated by
ChEMBL
Ligand
BDBM50254511
(CHEMBL468469 | Naltrexone-6-alpha-ol)
Copy SMILES
Copy InChI
Affinity Data
IC50: 32nM
Assay Description:
Inhibitory concentration was determined against delta-opioid receptor using [3H]- DPDPE radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI