Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50442143(CHEMBL2441274)Copy SMILESCopy InChI

Affinity DataKi:  0.251nMAssay Description:Inhibition of recombinant human FLAG-tagged ITK using biotinylated GST-SAM68 as substrate after 30 minsMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50442143(CHEMBL2441274)Copy SMILESCopy InChI

Affinity DataKi:  79nMAssay Description:Inhibition of Aurora-B (unknown origin) using 5FAM-PKAtide as substrate after 120 minsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI