Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beigene

US Patent

LigandBDBM200475(US9670231, 1.15)Copy SMILESCopy InChI

Affinity DataIC50:  4.40nMAssay Description:TBDMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Beigene

US Patent

LigandBDBM200475(US9670231, 1.15)Copy SMILESCopy InChI

Affinity DataIC50:  6.20nMAssay Description:TBDMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Beigene

US Patent

LigandBDBM200475(US9670231, 1.15)Copy SMILESCopy InChI

Affinity DataIC50:  6.80nMAssay Description:TBDMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Beigene

US Patent

LigandBDBM200475(US9670231, 1.15)Copy SMILESCopy InChI

Affinity DataIC50:  28nMAssay Description:TBDMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Beigene

US Patent

LigandBDBM200475(US9670231, 1.15)Copy SMILESCopy InChI

Affinity DataIC50:  49nMAssay Description:TBDMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI