Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50012187(INDIRUBIN 2)
Affinity DataIC50:  5nMAssay Description:Inhibition of GSK3beta (unknown origin) expressed in Sf9 cells using GS1 as substrate and [gamma32]ATP after 30 min by scinitllation countingMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University

Curated by ChEMBL
LigandPNGBDBM50012187(INDIRUBIN 2)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of 5-LO in human neutrophils assessed as product formation by cell-intact assay relative to control in presence of 2.5 uM A23187 ionophoreMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University

Curated by ChEMBL
LigandPNGBDBM50012187(INDIRUBIN 2)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of 5-LO in human neutrophils assessed as product formation by cell-intact assay relative to control in presence of 20 uM A23187/AA ionopho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Friedrich-Schiller-University

Curated by ChEMBL
LigandPNGBDBM50012187(INDIRUBIN 2)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human recombinant 5-LO assessed as product formation by cell-free assay relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed