Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50150521(CHEMBL3769556)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50150521(CHEMBL3769556)
Affinity DataIC50:  2.89E+3nMAssay Description:Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50150521(CHEMBL3769556)
Affinity DataEC50:  1.53E+3nMAssay Description:Agonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed