Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Cea

Curated by ChEMBL

LigandBDBM50303324((2S)-2-{[3-(4',5'-Dihydro-3'-phenyl-5'-isoxazolyl)...)Copy SMILESCopy InChI

Affinity DataKi:  13nMAssay Description:Inhibition of human somatic ACE C-terminal domainMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Cea

Curated by ChEMBL

LigandBDBM50303324((2S)-2-{[3-(4',5'-Dihydro-3'-phenyl-5'-isoxazolyl)...)Copy SMILESCopy InChI

Affinity DataKi:  910nMAssay Description:Inhibition of human somatic ECE1More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNeprilysin(Homo sapiens (Human))
Cea

Curated by ChEMBL

LigandBDBM50303324((2S)-2-{[3-(4',5'-Dihydro-3'-phenyl-5'-isoxazolyl)...)Copy SMILESCopy InChI

Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human somatic NEPMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI