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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by
ChEMBL
Ligand
BDBM50084284
(2-(4'-Bromo-biphenyl-4-sulfonylamino)-3-phenyl-pro...)
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Affinity Data
IC50: 19nM
Assay Description:
In vitro inhibition of matrix metalloprotease-2 (MMP-2)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Stromelysin-1
(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by
ChEMBL
Ligand
BDBM50084284
(2-(4'-Bromo-biphenyl-4-sulfonylamino)-3-phenyl-pro...)
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Affinity Data
IC50: 20nM
Assay Description:
In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by
ChEMBL
Ligand
BDBM50084284
(2-(4'-Bromo-biphenyl-4-sulfonylamino)-3-phenyl-pro...)
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Affinity Data
IC50: 21nM
Assay Description:
In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by
ChEMBL
Ligand
BDBM50084284
(2-(4'-Bromo-biphenyl-4-sulfonylamino)-3-phenyl-pro...)
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Affinity Data
IC50: 2.70E+4nM
Assay Description:
In vitro inhibition of matrix metalloprotease-9 (MMP-9)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by
ChEMBL
Ligand
BDBM50084284
(2-(4'-Bromo-biphenyl-4-sulfonylamino)-3-phenyl-pro...)
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Affinity Data
IC50: 5.60E+4nM
Assay Description:
In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Matrilysin
(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by
ChEMBL
Ligand
BDBM50084284
(2-(4'-Bromo-biphenyl-4-sulfonylamino)-3-phenyl-pro...)
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Affinity Data
IC50: 1.00E+5nM
Assay Description:
In vitro inhibition of matrix metalloprotease-7 (MMP-7)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI